Implementation of parenteral nutrition guideline and comparison of its early outcomes with conventional parenteral nutrition in Al-Zahra neonatal intensive care unit

Abstract

Intravenous feeding (PN) is a key component in the management of many newborns, especially low birth weight infants admitted to the Neonatal Intensive Care Unit (NICU). The aim of this study was to implement the clinical guideline of standard intravenous nutrition and compare its early consequences with the conventional method of intravenous nutrition in the neonatal intensive care unit of Al-Zahra Hospital in Tabriz.

Methods and Materials: This study is a cross-sectional study and the statistical population includes premature infants under 32 weeks or less than 1250 g hospitalized in the neonatal intensive care unit at Al-Zahra Hospital in Tabriz, which is divided into two groups before the establishment of the clinical nutrition guide. Intravenous (group 1) and after welcoming the clinical guide, intravenous nutrition (group 2) was performed with 70 samples for each group. The amount of energy prescribed and the same amount of macronutrient nutrients including carbohydrates, protein and fat, weight loss and weight gain of the baby, in two groups using statistical methods of description, chi-square test and using SPSS statistical software. 18 were subjected to experimental and statistical analysis.

Results: The results showed that the amount of energy and macronutrients (macronutrients) and the amount of glucose, amino acids and intralipid intravenous in group 2 were significantly higher than group 1. Calories received in group 2 with an average of 85.2 cal/kg/d and with a standard deviation of 17.8 and in group 1, 67.4 cal/kg/d with a standard deviation of 14.7 budget and statistical differences Was significant (P<0.001). Weight gain in the first 28 days of life and 28-day weight in group 2 means significantly more than group 1 budget. There was also a significant difference between the two groups in the correction time and the amount of added time in the removal time (P = 0.001). The rate of bacterial sepsis with positive blood culture was reported to be 7 in group 2 and 16 in group 1, which was statistically significant. (P=0.03)