The effect of incorporation the Bioactive Glass on the bioactivity properties of the Mineral Trioxide Aggregate

Abstract

Introduction: Bioactive glass is a bioactive substance that causes a bond between itself and tissues by creating a biological response on its surface. Due to the unique properties of bioactive glass, in recent years, extensive studies have been conducted on the application of this substance in dentistry. MTA(Mineral Trioxide Aggregate) has desirable properties for apico surgeries and has bioactive properties. Due to the properties of bioactive glass, it seems that the addition of bioactive glass improves the properties of MTA. Due to the lack of studies in this field, in the present study, certain amounts of bioactive glass were added to MTA and its effect on MTA bioactivity was studied.

Materials and Methods: Sol-gel method was used for bioactive glass synthesis. Then we added bioactive glass powder with specific proportions to MTA powder and performed related tests. Fifteen MTA samples were prepared and divided into three groups. In the first group, 20% by weight of bioglass powder was added to MTA, and in the second group, 10% and in the third group, pure MTA was used. The samples immersed in human tissue simulated solution SBF(Simulated body fluid) were placed at 37 ° C and incubated for three, ten, twenty, thirty, forty days, then the excess water was removed with the help of filter paper and then, the bioactivity of the samples and the formation of apatite layer were examined at regular intervals. Apatite formation was examined by X-ray diffraction (XRD), SEM and FTIR tests.

Results: The results of XRD, FTIR, and SEM tests showed the formation of a hydroxyapatite layer on the samples. Also, adding bioactive glass to MTA increases its bioactivity.

Conclusion: MTA alone has bioactive properties and by adding bioactive glass to it, the amount of MTA bioactivity increases. Also, with prolonged immersion time in SBF solution, part of the hydroxyapatite layer formed in SBF is solved.