Evaluation of the relationship between blood glucose changes before and after pediatric open heart surgery on length of stay in intensive care unit in Tabriz Shahid Madani Hospital

Abstract

Blood Glucose is an important substance in body that be used in methabolism of many organs. Perioperative hyperglycemia and hypoglycemia both have significant effect on post operative morbidity and mortality after cardiac open surgery. The aim of this study is to evaluate the relationship between blood glucose changes before and after pediatric open heart surgery on length of stay in intensive care unit. Materials and Methods: In this study, the target population included children under 15 years of age and undergo for open cardiac surgery with the help of a cardiopulmonary bypass pump at Shahid Madani Hospital in Tabriz in 2019. After obtaining the approval of the ethics committee of Tabriz University of Medical Sciences and obtaining informed written consent from all patients, 100 patients randomly choosen from addmission list of the hospital and were be observed .Blood glucose level in five stages from preoperation to 24 hour after operation was recorded. The relationship between preoperative blood glucose level and postoperative blood glucose level, length of hospitalization, perioperative ejection fraction of the heart and cardiopulmonary bypass pump time was reviewed. Results: The results show that there is no relationship between preoperative blood glucose level and lenth of hospitalization. Blood glucose level mean has its minimum level at before surgery and maximum level immediately after surgery. Then it decrease and have minimum level after surgery at 24 hour after surgery in our study.but this pattern is not related with lenth of hospitalization. Also this study shows that there is a negative relationship between preoperative glucose level and preoperative, operative, postoperative and first day after operation ejection fraction of heart that is a marker for heart contracture power. This relationship has its maximum significance with preoperative ejection fraction and minimum significance with postoperative ejection fraction. Also this study reveals that there is a negative relationship between preoperative blood glucose level and CPB time.