Comparison of early and 6-12 weeks postpartum diabetes screening in women with gestational diabetes mellitus

Abstract

One of the most important risk factors for type 2 diabetes mellitus (T2DM) is Gestational Diabetes Mellitus (GDM). To increase the screening rate among women with GDM, early postpartum test can be helpful. So, this study aimed at comparing the detection rate of postpartum diabetes in early and 6-12 weeks screening test in women with gestational diabetes mellitus. Patients and methods: ProQuest, Web of Science, Embase, PubMed, Cochrane, and Scopus were searched for English articles from January 1985 to August 2020. Two independent reviewers selected the eligible studies and the outcomes of interest were extracted. The quality of studies was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for diagnostic test accuracy studies. Sensitivity and specificity, negative likelihood ratio (NLR), and positive likelihood ratio (PLR) were calculated for the early postpartum OGTT. Results: Out of 1944 initially identified articles, 4 studies were included. The sensitivity and specificity of the early test were 74% and 56%, respectively and the PLR and NLR were calculated as 1.7 and 0.4, respectively. The sensitivity of the early test was higher than the specificity. This sensitivity and specificity can be used to distinguish normal cases from abnormal cases, including diabetes and glucose intolerance.