Comparative Efficacy of Different Concentrations of Triamcinolone Acetonid in Alopecia Areata

Abstract

The aim of the present study was to compare the effect of different concentrations of triamcinolone acetonide injection on alopecia areata. Materials and Methods: Patients with clinical diagnosis of alopecia areata who are randomly divided into three groups of 15 patients with different concentrations of triamcinolone acetonide at doses of 2.5 mg/ml, 5 mg/ml and 10 mg/ml were injected into the scalp lesion. Then, hair growth rate, response to treatment and side effects after treatment were evaluated. Results: The age group of 26 to 35 years had a higher frequency (40%) and most patients (62.2%) were male. 39 cases (86.7%) mentioned the history of stress and stressors in their daily lives. The mean age of onset of the disease in the studied patients was 35.11±11.88 years. The mean duration of illness (current attack) before treatment in the studied patients was 2.47±2.02 months. Nail changes were observed in 4 cases (8.9%) of the studied patients. There was a personal history in 5 patients (11.1%), 2 case of atopy, 2 cases of thyroid disorder and 1 case of vitiligo. In terms of family history, there were 9 cases of alopecia areata in the studied patients. Skin atrophy was observed in 12 cases (26.7%). 60% of patients improved after treatment and 57.8% of patients were completely satisfied.