A Comparison between the Effect of Dressing with Silver Sulfadiazine and Nitrofurazone on Burn Wound Infection among the Patients who are admitted to the Pediatric Burn Ward in Tabriz, 2005-2006.

Abstract

Abstract: Background & Objective: Burns remain an enormous public health problem throughout the world and especially in the economically developing countries. In Iran burn injuries causes significant morbidity and mortality, especially among the pediatric population. Infection remains the most common cause of death in the severely burned patient. The proper use of topical antimicrobial agents decreases the occurrence of bacterial resistance and sepsis. Nurses are the first providers that in charge of cleaning, debridement and daily wound care agents. The purpose of an active role in assessment and selection of wound care agents. The purpose of our study was to compare between the effect of dressing with Silver Sulfadiazine and Nitrofurazone on burn wound infection. Materials and Methods: This study was a Quasi Experimental study that carried out based on the convenience sampling for 9 month on the 94 cases who were admitted in the pediatric burn ward at the burn center of the Sina hospital, Tabriz, east Azerbaijan, 2005-2006. Research population was pediatrics who were admitted in this center and from among them, the patients having characteristics of research samples were selected as the samples for this study and were allocated in random in two groups (control and experimental). The tools were a questionnaire and a checklist. In this research one group was dressed with Silver Sulfadiazine cream and other group with Nitrofurazone and they were replaced once per day. For burn status assessment, in dressing exchange time, the wounds were considered regarding to the infection criterions and presence of epithelialization and granulation tissue. Also for each patient, bacterial cultures were made in three times by the swab. Descriptive analytical statistics methods were performed using the x2 test and t test by means of SPSS software (11.5). Results: Statistical analysis didn't show any significant difference between two topical antibacterial agents was rejected and it was seen that the efficacy of two groups based on the color, smell, secretion of burns wound and bacterial culture results (p>0.05). Also it wasn't seen any significant difference between two groups with regard to healing (p=0.658). Conclusion: In this study, our hypothesis based on a difference between two topical antibacterial agents was rejected and it was seen that the efficacy of two drug (Silver Sulfadiazine 1% cream and Nitrofurazone) were parallel. It indicated that over use of one drug can't be a reason for its efficacy. It seems that it should be pay more attention on selecting the drug for burnt patient treatment.