Evaluation of anti-fungal effect of effervescent centaining ginger in patients, with denture osteomatitis

Abstract

Introduction: Ginger has inhibitory effects on the growth of bacteria and fungi. The aim of this study was to evaluate the antifungal effect of ginger effervescent tablets in patients with denturesteomatitis. Materials and Methods: In this study, 18 patients were admitted based on clinical presentation and approval of an oral and prosthetic specialist in terms of denture stomatitis and according to the inclusion and exclusion criteria. The dentures of these patients were borrowed from them for 24 hours. The dentures were divided into three groups of six. The first group was placed in a solution containing ginger effervescent tablet (manufactured by Dana Pharmaceutical Company of Tabriz) for 3, 5 and 7 hours (2 hands of denture each time). The second group (dirt control) consisted of dentures that were placed in a dilute solution of 10% sodium hypochlorite for 30 minutes as a positive control group and the third group was immersed in distilled water. Data were analyzed using SPSS 17 statistical software and Mann-Whitney and Kruskal-Wallis tests. Results: In the hyporat group, after 30 minutes, the amount of bacteria, yeast and mold reaches about zero. In the group of ginger effervescent tablets, after 3 hours, there is a significant reduction in the number of bacteria and yeast. At 5 and 7 hours, there is a decreasing trend in the number of bacteria and yeast, but this amount is not statistically significant. There is no significant change in distilled water. Conclusion: Comparing the number of colonies in the group of 10% sodium hypochlorite and effervescent ginger tablets showed that in all three times the amount of colony in the ginger group is significantly higher than the hypochlorite group. As a result, it can be said that ginger has antimicrobial effects on denture stomatitis.