Complementary role of non-ECG gated 64-slice multidetector Computed Tomographic Angiography with echocardiography in diagnosis of congenital heart disease

Abstract

The aim of current study is to evaluate the complementary role of non-ECG gated 64-slice multidetector CTA with echocardiography and angiography in the diagnosis of CHD. Methods: In this study, 110 infants and neonates with CHD candidates for surgery were evaluated with echocardiography and CTA. Findings during surgery were considered as gold standard. Diagnostic accuracy, sensitivity and specificity of both methods were compared. Also angiography findings were available in 30 patients and all three modalities were compared in these patients. Results: diagnostic accuracy of echocardiography and CTA were 85.40% and 83.23%, respectively. Sensitivity and specificity of echocardiography and CTA in the diagnosis of intracardiac deformities were 98.90 and 78.57% and 89.57% and 78.57%, respectively and for extracardiac deformities were 90.53% and 100% and 94% and 100%, respectively. In the subgroup of 30 patients, echocardiography, CTA and angiography had accuracy of 87.75%, 85.71% and 82.65%, respectively. Sensitivity and specificity of echocardiography, angiography and CTA in the diagnosis of intracardiac deformities were 96.30%, 33.33%, 100% and 33.33% and 81.48% and 66.67% and for extracardiac deformities were 92.86% and 100%, 82.14% and 50% and 100% and 100%, respectively.