The effect of incorporation the Bioactive Glass on the solubility of the MTA

Abstract

Intrudoction: bioactive glass is bio-active material that forms a bond between itself and tissues by creating a biological response on its surface. Given its unique features and characteristics, bio-active glass has been extensively investigated by dental researchers in past years. MTA has shown favorable characteristics to be utilized for apico surgeries, however, it is identified with several down-sides such as longer setting times and vulnerability to be washed away by different liquids. In this regard, improving the performance of MTAs seems very likely to happen by addition of bio-active glasses. As the previous studies have not focused much on this aspect of bio-glasses, in this research we have investigated the effects of adding bio-active glasses on the MTA solubility. Materials and Methods: Sol-gel method is applied for synthesizing bio-active glass. Then, bio-active glass powder is added to MTA in appropriate portions and the effects are analyzed. In order to measure the solubility of the samples, we have complied with ISO 6876 methods which is approved by American Dental Association (ADA). 15 different samples of MTA are prepared based on the aforementioned ISO standards and are categorized in 3 main groups. First group will include 20% bio-glass in MTA, second group will include 10% and third group will be pure MTA. All samples are stored in 37±1 °C temperature for 24 hours and then they are placed in ringer serum. The samples are taken out of serums and after their drying process, they are weighed again. This process is conducted in three different time fashions: a) after 24 hours b) after 7 days c) after 30 days. Solubility of each sample is analyzed by comparing their initial and final weights. Results: The effects of time and percentage of added bio-active glass are measured using the repeated variance measures. Based on this variance the following results can be inferred: the interaction effect of the time and groups was not significant. Which means the variations of the MTA solubility in three groups were similar. The effect of time on MTA solubility was significant in three groups and solubility increased with time in all three groups. Mean difference of solubility was not statistically significant in three studied groups. Conclusion: Addition of 10% or 20% of bio-active glass (containing SiO2,CaO,P2O5, MgO,SrO) to MTA did not result in significant difference in its solubility (p-value=0.92) and, fortunately, it did not enhance solubility as well.