Biomechanical and Urodynamic Study of Heavy Lifting on Lower Urinary Tract System in Patients with Urinary Incontinency and Healthy Women

Abstract

The aim of this clinical trial is to study the effect of lifting heavy weights on the dynamic of lower urinary tract system using bio-mechanical and urodynamical simulation in women suffering urinary incontinence and normal ones. Methods and Materials: A single center study in urodynamic center of Imam Reza Hospital, Tabriz, Iran was conducted enrolling 51 participants ranged 30 to 65 years. Simple randomization was used to select participants from the target sample of healthy and incontinent women. Modeling of lifting heavy weights and holding them using a simulator device was used to understand the changes in intra-abdominal pressure, intra-vesical pressure and pressure of detrusor with empty and full bladder with anal and vesical sensors while running urodynamic study. Maximum Voluntary Contraction (MVC) of participants with full or empty bladder was measured and leakage was recorded if happened. Results: The mean age of 51 participants was 45.25 and the mean BMI was 28.96. Independent T-test showed a significant difference between patient and healthy group in both full and empty status of bladder in MVC, intra-abdominal, vesical and detrusor pressure. Paired T-test showed a significant difference between full and empty bladder in both group in all variables. Pearson test indicated MVC was highly correlated with vesical pressure in healthy group both in full bladder(p=0.006) and empty bladder (p=0.008)and intra-abdominal pressure in full and empty bladder 0.031 and 0.012 respectively. Regarding patient group MVC was highly correlated with abdominal pressure in empty bladder (p˂0000.1) and empty bladder (p=0.03). We observed three leaks in patient group while holding.