Psychometric properties of the quality of life in epilepsy inventory-10-P (QOLIE-10-P) in Iran – Persian version

Abstract

Background: To evaluate psychometric properties of the Persian version of the Patient Weighted Quality Of Life in Epilepsy inventory-10-P (PV QOLIE-10-P). Methods: Persian version was obtained from the original version by standard forward/backward translation. We assessed content validity, construct validity by factor analysis, internal consistency, test-retest reliabilities, criterion validity by calculating Pearson/Spearman correlation to the Persian version SF-36 inventory (PV SF-36), and discriminant validity by calculating Pearson/Spearman correlation to demographic features and epilepsy-specific characteristics.

Results: 155 adult epileptic patients were enrolled in the study. The 10 items of PV QOLIE-10-P were grouped into two factors: epilepsy effects/role function scale (driving, work, social, memory, physical effect and mental effect) and mental health scale (energy, depression, seizure worry and overall quality of life). The Cronbach’s alpha value was 0.859. Test-retest Analysis revealed statistically significant correlations for total score and the scales (correlation coefficient for total score, epilepsy effects/role function and mental health were 0.7, 0.66 and 0.7respectively). The Pearson correlation coefficient between total scores of the Persian version of QOLIE10-P and SF-36 was 0.822 (P < 0.001). The PV QOLIE-10-P was able to differentiate patients with marriage, education, job, seizure type, seizure frequency, and antiepileptic treatment.