Frequency and relationship of post stroke depression with lesion site and physical disability

Abstract

The aim of this study is to investigation of prevalence of post stroke depression and its relation with disability and brain lesion location. Materials and Methods: This was a descriptive-analytical cross-sectional study and after obtaining permission from the ethics committee, 100 patients with stroke for the first time in 2018-19 and referred to the neurology clinic of Imam Reza Hospital, Razi Hospital and the clinic of Tabriz University of Medical Sciences until one month after the stroke were selected and examined by available sampling method. These patients were studied by demographic and Beck Depression Inventory and Bartheldisability index. Results:In this study, the mean age (standard deviation) of the subjectswas 64.72(±13.1) yeras. The median (25th percentile and 75)of the Beck depression score and the Bartel disability score in the subjects studied was 0.11 (5.0-20.0) and 0.19 (15.0-20.0), respectively. Also, the frequency (%) of post-stroke depression in the subjects was 47 (47.0%).Most the location of the brain lesion in the subjects was in the Basal Ganglia Periventicular Lacunar area with 32 cases (32.0%) and then the Right MCA and Left MCA and areas with 27 cases (27.0%) and 23 cases (23.0%), respectively. Of all the variables related to demographic status, disability score, and location of the brain lesion, only the age variable had a statistically significant relationship with Beck's depression score (P-value = 0.005); That way for every one year increase in the age variable of the subjects studied, Beck's depression score decreased significantly 28/0 units. Other variables such as gender, disability score, and location of the brain lesion had not a statistically significant association with Beck's depression score in the subjects (P-value> 0.05).