Evaluation of density and variety in inflammatory cells and depth of infiltration in two types of lesions include lichen planus and oral lichenoid in patient who apply to pathology part of tabriz dental faculty

Abstract

Introduction: Histopathological diagnosis, but oral plan is based on tissue characteristics, which include hyperkeratosis or hyperparathyroidism, basal layer ejaculation and band infiltration such as lymphocytes, just below the epithelium, although in some cases these characteristics do not coexist. Due to the low number of published studies and the lack of focus of studies on whether the diversity and density of inflammatory cells differ in the two types of lesions - Lichen-Plan and Lichenoid, in this study to examine the differences in the diversity and density of inflammatory cells in the two types of lesions. However, lichen planus and lesions of the oral cavity were addressed. Materials and Methods: In this study, a cross-sectional study of 45 people with lichen planus lesions was used. For this purpose, individuals were selected in 3 different groups, including people with lichen planus lesions, with lichenoid lesions, and people with lichen planus lesions. Then, the study samples were collected from stained hematoxylin-eosin (H-E) slices obtained from the paraffin blocks of the archive in the Department of Oral, Maxillofacial and Maxillofacial Pathology of the Faculty of Dentistry, Tabriz. Finally, they were evaluated by 10× and ×40light microscopes. Finally, the data were analyzed using SPSS-23 software. All analyzes were performed at a significance level of 0.05. Results: In lichenoid cases, plasma cell and neutrophils had the highest number of inflammatory cells, with plasma cell having the highest number and no eosinophil specimens. In the erosive of the lichen planus of the erosive type, most of the inflammatory cells were plasma cell and there were no neutrophils or eosinophils. In reticular of the lichen planus , neutrophils, eosinophils, and plasma cells had the highest number of inflammatory cells, with more neutrophils than plasma cells and plasma cells more eosinophils. Analysis of Variance (ANOVA) tests did not show a significant difference in neutrophil, plasma cell and lymphocyte levels of the three types of lesions. The infiltration depth was similar in lichenoid and erosive lesions, but significantly lower in reticular lesions than in other lesions (p <.05). Conclusion. Analysis of Variance (ANOVA) tests did not show a significant difference in neutrophil, plasma cell and lymphocyte levels of the three types of lesions. The infiltration depth was similar in lichenoid and erosive lesions, but significantly lower in reticular lesions than in other lesions (p <.05).