Epidemiology and Clinical and Laboratory data and Prognosis Antibiotic Pattern of Shigellosis in Children Referred to Tabriz Children's Hospital in 2018

Abstract

This study attempts to determine the prevalence of shigellosis and the antimicrobial susceptibility pattern of isolated strains. Materials and Methods: This cross-sectional study, with 12-month duration, Between “March 2018” to “March 2019” was carried out on 93 children with Shigellosis disease. After obtaining the ethical related nessaries, all patients were reviewed because of diarrhea or infection that was admitted to Tabriz Children Hospital was reviewed. Results: 63 Of the 93 children with shigellosis, 63 (67.7%) were boys. The highest frequency was in the age group of 2 to 6/99 years (63.4%). The highest prevalence was in urban areas (94.6%). The most common clinical symptoms were fever (94.6%), diarrhea (94.6%), and seizures (15.1%), and decreased urinary output (14%). The most common serogroups respectively, were Shigella sonnei (87.1%), Flexneri (10.8%), and dysentery (2.2%). No specimens of Boyd's Shigella were found. The most common antibiotics respectively were Nalidixic Acid (91.4%), Co-trimoxazole (87.1%), Cefixime (78.5%), and Gentamicin (73.1%), Ampicillin (67.7%) and Cefotaxime (58.1%). The most susceptible to antibiotics were Chloramphenicol (93.5%), Ceftazidime (86%), and ciprofloxacin (41.9%). In prognosis, 88 children (94.6%) with complete remission and 5 children (5.4%) had been discharged with relative improvement and there were no reports of death.