Required doses of antiRH immunoglobulin in RH negative mothers with RH p neonates between tarumatic and non traumatic deliveries

Abstract

Among the many causes of fetal anemia, RH alloimmunization is the most common cause. In order to prevent RH isoimmunization, the use of Anti RH Immunoglobulin has been recommended to vary the dose required according to the amount of fetal-maternal hemorrhage. Materials and Methods: In this study, maternal fetal hemorrhage in Rh-negative pregnant women who had Rh-positive fetuses in two groups of traumatic and non-traumatic women was measured using Cliehover-Batch method and various factors affecting it. Bleeding rate was assessed. Finally, the required dose of immunoglobulin (rugam ampoule) was compared between the two groups. Results: In the traumatic childbirth group, the K.B test was positive in 2.8% and in the non-traumatic childbirth group, it was positive in 5%. Therefore, there was no significant difference between the two groups in the number and percentage of maternal-fetal hemorrhage (P <0.001). (P <0.05). Non-traumatic childbirth was 2.3. 0.8 ml. Statistical analysis of these results showed a significant difference in the rate of fetal-maternal hemorrhage between the two groups (p = 0.8, There was no statistically significant difference between those who experienced fetal-maternal hemorrhage, but after examining the volume of hemorrhage, there was a statistically significant difference in the need to inject additional doses. And studied there and traumatic childbirth is significantly higher than non-traumatic require higher doses had been given (p 0062/0 =)