Predictive factors of stroke in patients with Non-Alcoholic Fatty Liver Disease

Abstract

NAFLD is the most common form of liver disease. It is also a systemic disorder with cardiometabolic involvement. The most common cause of death in this disease is due to extra-liver causes, including cardiovascular disease, such as IHD and stroke. Finding the relationship between NAFLD and ischemic stroke will have major effects on general health. Because this association is also useful for assessing patients with acute ischemic stroke in terms of NAFLD, and patients treated with NAFLD are more invasive to prevent stroke. Methods: In this prospective cohort study, all patients with ultrasound diagnosis of fatty liver, in the absence of alcohol abuse and other liver disorders in association with fatty liver, were enrolled in the study and their data was recorded in a Data Base for 10 years (From 2007 to 2017). Lipid profiles, FBS, BMI and other data were extracted from the data base. Then, during a telephone call with patients, an ischemic stroke symptoms were asked, and if they were positive, they were recalled to visit free of charge. Finally, with the completion of patient information, the data were analyzed using the statistical software STATA.15.1 Results: In the statistical analysis, independent t-test, the mean lipid profiles parameters (TG, CHOL, LDL, HDL), glycemic index (FBS) and anthropometric factor (BMI), and age and fatty liver grades were compared among people with stroke and individuals without stroke. the FBS, BMI and age were significantly higher in patients with stroke (P-value <0.05)