Evaluation of effect of varicocele on sperm survival in vitro

Abstract

The aim of this study was to evaluate the fertility potential and sperm function with the help of sperm survival test and optimization of varicocele surgical indications in fertile men with normal sperm analysis, idiopathic infertile Oligoasthenospermia patients, infertile Oligoasthenospermia patients with unilateral varicocele and in patients with infertile normospermia with unilateral varicocele Comparison. Materials and methods: In this study, patients who referred to Urology Clinic of Sina Medical Center of Tabriz University of Medical Sciences in 2017, were evaluated in 4 groups of 30 subjects. The first group was infertile patients without varicocele in the examination; the second group had unilateral varicocele and had sperm analysis with oligostenospermia, third group of patients with one-way vikocelin, and normal sperm analysis and the fourth group of healthy subjects. All people under examination. A questionnaire containing demographic data including age, marital status, duration of infertility, drug use, etc., was completed by patient information. Then sperm samples were collected. Also in the laboratory, sperm count was evaluated to evaluate the sperm function. In this test, at 0, 4, 12, and 24, sperm motility was investigated. Finally, all of the data were entered into SPSS statistical software version 18 and analyzed statistically. Results: In this study, the highest concentration of sperm with 65.86 million in patients with infertility and without varicocele was observed. Also, in examining the speed of A sperm grading, although the rate in idiopathic healthy and infertile people was higher than the other two groups, it did not show significant difference. But at Grade B speed, the average speed was higher in healthy subjects. Overall, high rates were seen predominantly in healthy individuals and then in patients with idiopathic infertility. It was also observed that sperm survival was associated with infertility in the patient, and patients with infertility, despite the lack of varicoceles, did not have a favorable sperm survival condition.