The survey of Echocardiographyc findings in patients with kawasaki disease who reffered children’s hospital in 12 years

Abstract

Kawasaki disease is a vasculitic syndrome of unknown etiology: Kawasaki is a limited disease. Today, 20% of children with untreated Kawasaki disease develop cardiac aneurysm and 0.1% to 2% of these children die. In the United States, the syndrome is now overtaken by rheumatic fever and is considered to be the first cause of acquired heart disease in children under 5 years of age. This study aimed to investigate the prevalence of each clinical manifestation and laboratory findings of Kawasaki disease in Tabriz Children's Hospital is being operated. This study also examined the rate of heart involvement in patients with Kawasaki disease. The results of this study will be compared with those from other regions and countries. Materials and Methods: This cross-sectional descriptive study was performed on Kawasaki patients referred to Tabriz Pediatric Educational Center from 2003 to 2016. Diagnostic criteria included fever, morbilliform rash, nonspecific bilateral conjunctivitis, extremity scaling, oral mucosal and pharyngeal changes. Age, sex, clinical and paraclinical changes of patients were also evaluated. The most important organ involved is the cardiovascular system. Therefore, the aim of this study was to evaluate its cardiac complications during a twelve-year follow-up follow-up, during a twelve-year period (2003-2016). A list of appropriate variables is designed and the demographic, clinical, laboratory, and cardiac complications of the patients are recorded. The variables were considered based on the contents of the references and all clinical signs and symptoms. Echocardiography was used to evaluate the cardiac symptoms and according to the results of the echocardiography, a variety of cardiac disorders were collected, evaluated and followed up. Echocardiographic findings of one year after clinic and first and second echoes were extracted from patient records. Results: Frequency of cardiac findings in the patient with Kawasaki syndrome was correlated with the presence of extremity edema and morbilliform rash in the clinical examination. The incidence of cardiac involvement in the first echo was 42.3%, in the two weeks later was 35% and in the one year later 3.8%. The most common complication is LCA and RCA dilation.