Validity of SvO2 and PvO2 diagnostic Value in O2 Content Measurement in pediatric patients

Abstract

Introduction: Arterial oxygen and oxygen saturation measurements can be used together to measure the amount of oxygen supply and consumption, and then determine the oxygen content of the body. The aim of this study was to evaluate the validity of SvO2 and PvO2 in O2 content measurement in children hospitalized with respiratory distress. Materials and Methods: In this cross-sectional study, 80 children who had been diagnosed with respiratory distress were included in the study according to the criteria for entering and leaving the study. Demographic information such as age, gender was recorded in the data collection form, designed by the researcher. In order to determine the amount of SaO2 and PaO2 in the arterial blood sample, a standard blood sample was prepared to determine the amount of hemoglobin, SvO2 and PvO2. The gold standard was the determination of O2 content in arterial blood samples. All specimens were examined by a blood gas analyzer. It was then calculated using the formula of O2 Content values. Determination of sensitivity, specificity, positive and negative predictive value was used to determine the validity of SvO2 and PvO2 by diagnostic analysis methods. Results: In this study, the patients with mean age were 5.15 ± 4.20 years. 62.5% were male and 38.5% were female. The values of O2 content of arterial and venous contents were 14.13 ± 3.05 and 11.94 ± 3.04. The use of venous O2 content instead of the arterial have sensitivity of 90.91%, specificity of 67.24%, positive diagnostic value of 51.28%, and negative diagnostic value of 95.12%. SvO2 and PvO2 in diagnosis of O2 content have sensitivity of 80.5% and 71.08% respectively, and specificity of 80.5% and 78%, respectively. Conclusion: SvO2 and PvO2 have a good validity in evaluating the O2 content of patients admitted to PICU. So that SvO2 has a sensitivity and specificity of above 80% and PvO2 has a sensitivity and specificity of over 70%.