The effect of Biotin and Bepanthene on hair loss in patients with androgenetic alopecia

Abstract

Androgenetic alopecia (AGA) or male pattern hair loss is a type of hair loss disorder caused by dihydrotestosterone (DHT), a potent form of testosterone. Without treatment, patients will have progressive hair loss. Androgenetic alopecia is common in all societies, and its incidence increases with age. So far only two therapeutic agents have been approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for the treatment of AGA: topical minoxidil and oral finasteride (1 mg daily). It is also recommended to prescribe some vitamins such as vitamin B5 and B7 to prevent hair loss.

Objective: The aim of this study was to evaluate the effect of biotin and dexpanthenol on hair loss in patients with androgenic alopecia.

Methods: In this study, patients with androgenic hair loss were divided into one control group and two sample groups after presenting the results of the examination and diagnosis of a dermatologist. The control group was treated with 5% minoxdil solution and 1mg finasteride tablets, the first group received biotin ampoules in addition to the control group, and the second group received a baseline treatment plus biotin and dexpanthenol ampoules. All three groups were evaluated for decreasing hair loss and increasing the number and thickness of hair. Results: Comparison between the three groups mean hair loss and mean hair diameter and percentage of hair growth during the four times in the biotin and biotin + dexpanthenol group were significantly better than the control group (p <0.05).

Conclusion: Based on the results of this study, it can be concluded that biotin and dexpanthenol can be helpful along with the routine treatment of androgenic alopecia.