Evaluation of the expression profile of micRNAs which regulate both stemness and metastasis in stem cells derived from breast cancer

Abstract

Hence, this study provides new insights for targeting core-regulatory of miRNAs in breast CSCs to target both self-renewal and metastasis potential and eradication of breast cancer. Here we suggest that the combination of miR-204, miR-200c, miR-34a and miR-10b with the formation of a regulatory regulatory network to induce self-induction and EMT in cancer stem cells, as well as the survival rate of patients with breast cancer influence.