Molecular analysis of single nucleotide polymorphisms Asp 299 Gly and Thr 399 Ile TLR4 gene in patients with Hydatidosis

Abstract

hydatidosis has not yet been sufficiently elucidated in postoperative patients. Methods and Materials: In this case-control investigation, 80 patients from Iran, including 40 with acute hydatidosis (AH) and 40 with recurrent hydatidosis (RH),and 80 ethnically matched controls were evaluated from February 2015 to February 2017. Hydatidosis patients were confirmed using radiological, immunological, and histopathological examinations Genotyping of Asp299Gly and Thr399Ile of TLR4 single-nucleotide polymorphisms was determined by restriction fragment length polymorphism, sequencing, and phylogenetic strategies.