Measured and modelled electrical bio-impedance inside the human normal and malignant bladder epithelium

Abstract

Computational modelling of the electrical properties of the bladder tissue may be helping us as a diagnostic technique. Unlike normal oesophagus and cervix, the urinary bladder tissue is distensible and lined with transitional epithelium (cell shape changes from cuboidal to squamous) depending on the state of contraction or distension. Changes in cell shapes and arrangements are expected to influence the electrical properties of the tissue. Therefore, a numerical technique, Finite Element Analysis (FEA) was used to model the electrical properties of the bladder tissue in order to predict the electrical bio-impedance spectrum. The modelled data was compared with the experimental results. é 2007 Inderscience Enterprises Ltd.