Effect of aerobic activities in hypoxia situations on interleukin-6 and interleukin-10 serums of active young men

Abstract

The purpose of this study is to investigate the effect of physical activity on cytokinesIL-6 and IL-10 in serums of human being. Eight active young men with mean age of 23.33±1.56 years old, 64.16±3.14kg weight and 176±1.76cm height participated in four aerobic activity sessions including running in span of 30min with intensity of 70% maximal heart beat rate in four normoxia and hypoxia situations (at altitudes of 2750 m, 3250 m and 3750 m). Before, immediately after and 1 hour after activities, blood sample were collected. Analyzing data using mixed models indicated there isn't any significant difference between normoxia and hypoxia for concentrations of both cytokines (P>0.05). All of 4 activity sessions led to significant decreases in IL-6 (P<0.05). Also, decrease in IL-10 after activity in normoxia situation at 3250 m altitude was insignificant (P>0.05). Most of previous founds indicated IL-6 reduction in hypoxia situations and only one research like the present study didn't observe these reductions. Although, some probabilities have declared about this informational contrariety in the present study, but there're some evidences to deny them. There're neither in access information nor consistent results about effect of hypoxia situation on IL-10. In a manner that both increase and decrease in IL-10 were reported in hypoxia situations. In order to carry out an accurate conclusion, rather researches which control other influencing variables are required. © IDOSI Publications, 2012.