Dose supplemental zinc prevents recurrence of febrile seizures?

Abstract

Objective: Febrieseizures (FS) are the most common form of seizures in children revious studies have suggested that zinc may play a role in the prevention of FS. However there is limited information on the preventative effects of zinc against FS. This study aimed to determine whether prescribing zinc supplements could prevent FS. Materials & Methods In a randomized, placebo-controlled trial, 100 children who had experienced simple FS for the first time were recruited. Children in the case (50 patients) were orally administered1mg/kg/day zinc sulfate for 1 year, and children in the control group (50 patients) received a placebo. Serum zinc levels in both the control and case groups were measured at the start and at the end of the study, and recurrent cases of FS were recorded. Results: The case group consisted of 29 boys (58%) and 21 girls (42%) with a mean age of 2.06 آ± 0.83, and the control group consisted of 31 boys (62%) and 19 ound bet ldren (16 m crea increm recurrent FS within a year. Supplemental doses of zinc (1mg/kg/day) reduced the rate of febrile illnesses, but did not prevent the recurrence of FS.