Corneal biomechanical properties distribution in myopic population

Abstract

AIM: To evaluate distribution of corneal biomechanical measurements in normal myopia and myopic-astigmatism population. METHODS: One hundred and eighty eyes with myopia and myopic-astigmatism candidated for laser refractive surgery were included in this study. Complete examination of anterior and posterior segments, manifest refraction spherical equivalent (MRSE), Orbscan and Zywave were performed preoperatively. Ocular response analyzer (ORA) was used to measure corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg) and corneal compensated IOP (IOPcc). Distribution of all corneal biomechanical properties and correlation between these parameters and MRSE, age and sex were determined. Statistical analysis was performed using SPSS 17 software and a P-Value less than 0.05 was considered significant. RESULTS: Mean age was 28.20آ±6.78 years. Mean MRSE was -4.21آ±1.19D. Mean CH, CRF, IOPg and IOPcc was 10.00آ±1.28mmHg, 10.17آ±1.45mmHg, 15.71آ±2.67mmHg and 16.68آ±2.41mmHg respectively. 28.4% of all myopic population had CH about 10mmHg, and 71% had CH, 9mmHg up to 11mmHg. CRF in 25.9% of myopic population was 10mmHg, and in 48.7% was 9mmHg up to 11mmHg. There was very poor positive correlation between MRSE& CH (Rs=0.001, P=0.71) and MRSE& CRF (Rs=0.01, P=0.18). CONCLUSION: Our study demonstrated the distribution of corneal biomechanical properties (CH, CRF, IOPg, IOPcc) in normal myopia and myopic-astigmatism population in Iran, and confirmed that, there was no statistically significant correlation between CH, CRF and MRSE, age and sex but there was significant correlation between IOPg, IOPcc and formerly mentioned parameters.