Application of 99mTc-DTPA radiotracer in Persian cat's renal scintigraphy

Abstract

Purpose: To evaluate the suitability of 99mTc-DTPA as a radiotracer in Persian cat's renal scintigraphy. Methods: twelve adult healthy Persian cats were selected. For scintigraphy, the animals were anesthetized and 99mTC-DTPA was injected via the femoral vein as a bolus at a dose of 1.5 mCi. Immediately after intravenous injection of radiotracer, scintigraphic operation was conducted on the renal organ. dministration of the radioisotope and accumulation of radioisotope in the tissues was monitored by specific imaging theemanating Results: Distinct scintigraphic scans were obtained using 99mTC-DTPA. Visual comparison of the scans indicates that there was no significant difference in the accumulation of radiotracer. In dynamic scans, symmetric and concurrent distribution of 99mTc-DTPA in the kidney was observed. Conclusion: The results show that the radiopharmaceutical 99mTc-DTPA is suitable for use in Persian cat's renal scintigraphy, and this makes it potentially useful in research and clinical practice. é Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria. All rights reserved.