The effect of Jessner's solution peel on acne vulgaris

Abstract

Introduction: Acne is a common skin disease, if remains without treatment, permanent scars and pigmentation would be anticipated. Comedon formation has a basic role in the inflammatory lesions and permanent acne scars. With regard to the mechanism of superficial peeling that can be attributed to the disconnection of the bands between keratinocytes, Jessner solution can be used in the treatment of acne. Materials & Methods: This study was performed on 15 patients with mild to moderate acnes. The patients enrolled, were treated with Jessner solution in 4 sessions with one week intervals. The surface should be washed with alcohol before treatment. After appearing the erythema, the procedure must be stopped and the solution be washed off. Patients should be advised to use sun block creams. Jessner solution is composed of various compounds such as salicylic acid 14% resorcinol 14% and lactic acid 14% in the ethanol base. Application of Jessner's solution with a sable brush on a monthly basis for 3 months to the partial face or to the entire face will freshen the skin and slough comedons. Results: In this study we compared the numbers of comedons, pustules and inflammatory papules in the face before and after treatment. The average number of comedons was 72.73 before and 36.93 after treatment. The average erythematous papules was 32.4 and 20.46 before and after treatment respectively. The average number of pustules reduced from 9.13 before treatment to 6.4 after that. In the aggregates, the number of comedons, erythematous papules and pustules reduced significantly in this study. Conclusion: Regarding to the simplicity, cost effectiveness of this method and also its safety, this procedure can be an appropriate alternative for treatment of acne.