STUDYING ANALGESIC EFFECT OF PREINCISIONAL INFILTRATION OF LIDOCAINE AS A LOCAL ANESTHETIC WITH DIFFERENT CONCENTRATIONS ON POSTOPERATIVE PAIN

Abstract

Objective: Preincisional infiltration of anesthetics into surgical wounds may be effective in various elective surgeries. The aim of this study was to asses the effect of lidocaine infiltration with different concentrations in relieving post operative pain in tubectomy patients. Methodology: This is a placebo controlled double blind trial, performed on 80 female patients candidated for tubectomy with general anesthesia between the years 2006-2007. The study was conducted in Tabriz University of Medical Sciences, Tabriz, IRAN. The patients were consecutively randomized into four groups. Three groups which consisted of 20 patients each received lidocaine infiltration before skin incision with different concentrations (0.5%, 1%, 1.5%) and were examined for intensity of feeling pain and the duration of analgesia in comparison to the fourth group or control group (20 patients), in which normal saline solution infiltration was used. In this study the intensity of postoperative pain was assessed using VRS (Verbal Rating Scale). Data collection was done using the questionnaire, and collected data was analyzed by student t-test, using SPSS software and descriptive statistical program. P<0.05 was considered significant. Results: Average duration of analgesia was five hours about groups I, 3:30 hours for group II and it reported to be 20 hours in group III. In the control group, however, it was only an hour. Conclusion: Preincisional local infiltration of lidocaine 1.5% is an effective, simple and cost-effective approach for postoperative pain relief among tubectomy patients.