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Delivery of Quercetin as an Antioxidant Agent to Cancer Cells by Single-walled Carbon Nanotubes

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Date
2011
Author
Dolatabadi, JEN
Jamali, AA
Hasanzadeh, M
Razmaraii, N
Omidi, Y
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Abstract
Carbon nanotubes are made up of carbon atoms arranged in a series of condensed benzene rings and wrapped into a tubular form. These materials due to some qualities such as high specific surface area, unique electrical and electronical properties are used in many applications as catalyst base, polymers mechanical strengthening, composites, electronical devices production and drug delivery. This work speculates on methods of design, synthesis, and quercetin delivery as an antioxidant agent that its anticancer function has been reported, by single-walled nanotubes into cancer cells and their detection method. In fact, we introduces the concept of "functionalization partitioning" of single-walled carbon nanotubes (SWCNTs), i.e., imparting various chemical species, such as poly (ethylene glycol) (PEG), quercetin with different functionalities onto the surface of the SWCNTs. And we will discuss how binding of molecules to SWCNTs and their release can be controlled by varying the pH.
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http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/50438
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