Association between hormone replacement therapy and occurrence of breast cancer

Abstract

Using hormone replacement therapy for relieving menopausal symptoms and also for preventing some diseases such as hip fractures had led to a widespread use of it in postmenopausal women but there is a concern about risks of breast cancer occurrence using HRT. In this study, 1000 women older than 40 years old without any clinical symptoms were selected. They were referred to a radiology center for a screening mammography. By using a questionnaire the information about using HRT was gathered. 16.7% of cases were using HRT and 83.3% had no history of using HRT. Among 1000 cases, 13 mammograms had signs of malignancy. In these cases 7.7% was using HRT and 92.3% didn't have any history of using HRT. It was concluded that there isn't any statistically significant association between the development of breast cancer and using HRT (P=0.604). [Rahmani SH, Ahmadi S, Moghbel A, Navali N, Khodaverdi Zadeh H. Association between hormone replacement therapy and occurrence of breast cancer. Life Sci J 2012;9(4):3787-3789] (ISSN: 1097-8135). http://www.lifesciencesite.com. 562