Study on uterine artery blood flow in myomatous uterus

Abstract

Leiomyomas constitute the most common female pelvic tumor, becoming increasingly prevalent with age. Although transabdominal ultrasound is usually used for observation of the large uterine tumors outside the focal zone of the transvaginal transducer, but transvaginal ultrasound is the standard imaging modality for this purpose. Recently with introduction of transvaginal color Doppler ultrasonography some studies have been performed on uterine artery blood flow in myomatous uterins, however these studies are scanty. Our object in this study is the determination of probable particular effects of leiomyoma on blood flow in uterine arteries. In this cross sectional study 50 women with myomatous uterine and 50 healthy volunteer woman were enrolled in the study. Transvaginal color Doppler was used for observation of uterine arteries and vascularity of myomas. The mean uterine volume was significantly lower in control group (97.00 +/- 37.71 cm3) than in cases (3S1.16 +/- 222.94 cm3). The mean peak systolic velocity (PSV) was significantly lower in control group (36.42 +/- 9.28 cm/s) than in case group (49.34 +/- 16.37cm/s). Significant correlation between uterus volume and PSV was not seen in control group but medium positive correlation between mean uterus and mean PSV was seen in case group. Mean pulsatility index (P1) was 1.59 +/- 0.36 in case group and 2.40 +/- 0.46 in control group. Significant correlation between mean uterus volume and mean pulsatility index ( PI) in study group was seen. Mean resistance index (RI) was 0.74 +/- 0.19 in case group and 0.85 +/- 0.23 in control group. No correlation was found between uterine volume and number of myomas. Only in %34 cases myomas artery was detectable and mean myomas artery RI was 0.57 +/- 0.18. We observed significant differences between uterine arterial Doppler indices in patients with myomatous uterins and control group. The presence of myomas result in uterine volume increasing and uterus Volume has significant correlation with PI decreasing. Also PSV has significant correlation with uterine Volume. This significant difference suggests that, we can use serial measurements in duration of treatment in monitoring response to medical treatment. [Fatemeh Ghaterh Samani, Roghaieh Jabbary, Omid Mashrabi. Study on uterine artery blood flow in myomatous uterus. Life Sci J 2012;9(4):583-586] (ISSN:1097-8135). http://www.lifesciencesite.com. 88