Antioxidant, Antimicrobial and Physicochemical Properties of Turmeric Extract-Loaded Nanostructured Lipid Carrier (NLC)

Abstract

The objective of this research was to encapsulate turmeric extract as a water-insoluble bioactive material by nanostructured lipid carrier (NLC). Turmeric extract loaded NLC (T-NLC) was produced by high shear homogenization method. The average size of T-NLC was 112.4 nm and it showed good physical stability, and a sustained release pattern. Higuchi model fit in vitro release of turmeric extract from NLC the best. The antioxidant activity of T-NLC was significantly higher than free turmeric extract. The results of microbiological tests by agardilution method showed that NLC had higher antimicrobial activity than free turmeric extract against all examined gram negative bacilli microorganisms. The results indicate that T-NLC can be used in food products with high functional effects.