Cytomegalovirus Gastritis in Renal Graft: Case Report

Abstract

Introduction: Cytomegalovirus (CMV) is an important pathogen, and its infection develops in 70% to 90% of transplant patients. Upper gastrointestinal (GI) symptoms in the solid organ recipient are common (20%) and clinical signs are more serious in 10% of cases. Case Presentation: This study reports on a 30-year-old male with end-stage renal disease that had undergone kidney transplantation from a CMV negative donor at Imam Khomeini hospital, Urmia, Iran during June 2013. After 1.5 months, he was admitted with fever, generalized body pain, oral aphthous ulcers, and epigastric pain accompanied by malaise. Endoscopic examination and clinicopathological investigations revealed multiple antral erosions with surrounding erythema. Management and Outcome: The patient was started on Intravenous (IV) ganciclovir 5 mg/kg per day, every 12 hours initially for 3 weeks. Afterwards, the general condition of the patient improved. Discussion: The colon and stomach were the most common sites of the gastrointestinal infection, yet localization to the gastric antrum is not common.