Cytosensing of cancer cells using antibody-based molecular imprinting: A short-review

Abstract

Rapid and effective differentiation between normal and cancer cells is an important objective for the diagnosis, prognosis and theranpsis of tumors. This short review highlights some of the most recent developments on the application of molecular bioimprinting in detection of cancer cells using antibody based cancer cell recognition method. The particular emphasis of this review is on sample-to-answer devices and approaches that enable down-stream investigation of the properties of the cells. Given the speed, portability, sensitivity and selectivity achieved using molecular bioimprinting technology on cancer cell monitoring, these methods hold the promise of transformative change in clinical practice. (C) 2017 Elsevier B.V. All rights reserved.