A New Method for Non - traumatic Epistaxis Management Using Celox (R) Dressing: A Randomized, Clinical Trial

Abstract

Background: Today, one of the newest products used to control any bleeding is band Celox (R). Objectives: The current study aimed at evaluating the therapeutic effect of the Celox (R) bandage to manage non - traumatic epistaxis in the emergency department (ED). Methods: In the current randomized, clinical trial, 150 patients with non -traumatic epistaxis admitted to the ED in Imam Reza and Sina hospitals affiliated to Tabriz University of Medical Sciences were enrolled. All patients were randomly divided into 2 groups: group 1 dressing with the Celox (R) band and group 2 dressing with anterior nasal tampon. The convenient sampling method was employed. Bleeding control (minute), patients' satisfaction, and lack of rebleeding within the first 24 hours of administration were compared between the 2 groups. Results: There was no statistically significant difference between the 2 groups in terms of demographic variables, vital signs, and paraclinical testing results (P > 0.05). With respect to the control of bleeding in the first 5 minutes after management, 93.3% of the bleeding was controlled in the Celox (R) and 96% of the bleeding was controlled in the anterior tampon groups (P = 0.467). The satisfaction level of the patients in the Celox (R) group was greater than that of the tampon group, and the difference was statistically significant (P < 0.001). Lack of rebleeding within 24 hours after management had the most significant effect on the patient satisfaction [odds ratio (OR) = 3.969]. Conclusions: Based on the results of the current study, there was no significant difference in bleeding control and the success rate between the 2 groups of the study. Ease of usage, however, makes Celox (R) a better alternative to control epistaxis. Furthermore, the treatment of epistaxis with Celox (R) leads to greater satisfaction levels.