Rapid Intravenous Rehydration to Correct Dehydration and Resolve Vomiting in Children with Acute Gastroenteritis.

Abstract

The objective of this study is to evaluate the effect of rapid intravenous rehydration to resolve vomiting in children with acute gastroenteritis.This randomized control trial was conducted in the pediatric emergency department in a tertiary care center in Tabriz, North-West of Iran. The study participants' were 150 children with acute gastroenteritis and vomiting who were moderately dehydrated, had not responded to oral rehydration therapy and without any electrolyte abnormalities. 20-30 cc/kg of a crystalloid solution was given intravenously over 2 hours and the control group was admitted in the emergency department (ED) for a standard 24 hour hydration. Effectiveness of rapid intravenous rehydration in the resolution of vomiting in children with acute gastroenteritis was evaluated.In 63 children of the intervention group (out of 75) vomiting was resolved after rapid IV rehydration and they were discharged. Among them, 12 that did not tolerate oral fluids were admitted. In the control group, 62 patients' vomiting was resolved in the first 4 hours after admission, and there was no significant difference between the two groups regarding resolution of vomiting.Rapid intravenous rehydration in children with moderate dehydration and vomiting due to gastroenteritis is effective in reducing admission rates in the ED.Bu çal??man?n amac?, akut gastroenteritli çocuklarda, h?zl? intraven?z rehidratasyon tedavisinin kusma أ¼zerine etkisini de?erlendirmektir.Bu randomize kontrollأ¼ çal??ma ?ran'?n Kuzeybat?s?ndaki Tebriz ilinde أ¼çأ¼ncأ¼ basamak çocuk acil servisinde gerçekle?tirildi. ?al??maya orta derecede dehidrate, elektrolit anormalli?i olmayan ve oral rehidrasyon tedavisine yan?t vermemi? akut gastroenteritli 150 çocuk kat?ld?. ?ki saat içinde intraven?z yolla 20-30 cc/kg kristaloid ç?zelti verildi ve kontrol grubu standart 24 saatlik hidrasyon için acil servise al?nd?. Akut gastroenteritli çocuklarda, h?zl? intraven?z rehidratasyon tedavisinin kusma أ¼zerine etkisi de?erlendirildi.Mأ¼dahale grubundaki 75 çocu?un 63'أ¼nde h?zl? IV rehidrasyondan sonra kusma geçti ve hastalar taburcu edildi. Bu çocuklar?n 12'si oral s?v?lar? tolere edemedikleri için hastaneye kabul edildi. Kontrol grubunda 62 hastan?n kusmas? hastaneye kabulden sonraki ilk 4 saat içinde geçmi? olup, iki grup aras?nda kusman?n geçmi? olmas? aç?s?ndan herhangi bir anlaml? farkl?l?k yoktu.Gastroenterite ba?l? orta derecede dehidratasyon ve kusmas? olan çocuklarda h?zl? intraven?z rehidrasyon acil servisten yat?? oranlar?n? azaltmada etkilidir.