The comparison of IL8 levels in saliva than in the two regions, the North west of Iran with different degrees of air pollution-in 1393

Abstract

Air pollution in cities is permanent and serious threat to public health and the environment that in the form of acute and chronic health affects different body organs and systems. These effects include high or minor respiratory stimulations, heart disease and chronic respiratory, lung cancer, acute respiratory infections in children and chronic bronchitis in adults, worsening lung and heart disease and asthmatic attacks. Various organic and inorganic compounds found in the saliva secretion that varies due to environment changes. Aim: The purpose of this study was to compare the IL8 in saliva in the two regions, the North West of Iran with different degrees of air pollution - in 1393. Methods: After selection of qualified subjects, the exact age of each children specimen was recorded and saliva was collected in special bottles. In this method (Spitting) was used to collect saliva in the two groups. The random sampling was based on the clustering of 44 persons per group. Saliva of the subjects was collected during the morning 11-9. In addition to banning orders on 90 minutes before taking any food ingredient was tested in individuals. After collecting saliva samples were transported to the laboratory and by ELISA method and kit for each protein, the protein content per unit volume of each specimen was measured and recorded. Each group descriptive data were calculated to evaluate the mean difference between groups were used to perform independent T test and non-parametric tests, Kolmogorov test, for data normality. Result: The results showed that the mean standard deviation (Mean SD) levels of IL-8 in saliva for children in this age range and in the city of Tabriz city nomads respectively 291.826.5 and 108.4 11.04 pg ml saliva that an increase of nearly 3 times the amount of IL-marker early in the industrial city of Tabriz with High air pollution than children affected by clean air and clean Kaleibar non-industrial city. Conclusion: The overall results suggest that the direct relationship between the level of salivary IL-8, and the significant level of air pollution in the region was Tabriz. These findings confirms that air pollution in industrial cities such as Tabriz, unlike cities such as Kaleibar in a healthy and clean air, stimulate production and increased levels of salivary IL-8 between the ages of 9 to 11-year-old has played a role.