Evaluation of titanum releasing in gingival sulcular fluid around dental implants

Abstract

Introduction: Dental implant is a piece of titanium, that is often in the form of tooth root placed into the jawbone. Despite the high corrosion resistance of titanium there is evidence of titanium release and aggregation in adjacent tissues. Although titanium has high biocompatibility, tissue reaction varies from mild to severe reactions to a different types of titanium. The aim of this study was to evaluate the gradual release of titanium in GCF around dental implants. Methods & Materials: In this study, 25 subjects with age range of 30-40 years that had received one unit fully osseointegrated posterior implant and in the case of not having more than 2mm gingival height above the fixture entered the study. Smoker subjects and those who were using different mouthwashes were excluded. GCF sampling performed immediately before crown delivery, one week, one month and two months, after the prostheses were delivered. For the data analysis SPSS16 was used. To compare the time of stimulation of the cells and MRNA, mean, SD and Aone way ANOV and TUKEY post hoc test was used. To measure the ELISA results the curve export software was used. The P-value of less than 05/0 was considered statistically significantResults: The results showed that the amount of titanium infiltration in GCF after placing the titanium abutments is high. In patients who had used titanium abutments the inflammatory factors such as IL-1, IL-6, TNF increased compared with the control group. The amount of titanium in the period after a week had a significant increase over other intervals as well as immediately before the crown was the lowest compared to other intervals. This study and previous studies, also showed that the infiltration rate of titanium in GCF in first month after delivery reaches its highest level and the infiltration rate decreases with time, so that is the lowest in 2 months after delivery.Conclusion: Amount of titanium infiltration has the highest level during first month of delivery, and the lowest level 2months after deiovery, in fact the amount of titanium in GCF decreases through time.