Comparison of Heart Rate and Blood Pressure after administration of anesthesia agent with and without Vasoconstrictor

Abstract

Local anesthetic agents have been used in dentistry offices for a long times. other agents are added beside the anesthetic drug in the cartridge of these agents for different aims such as prolonging the shelf time,Prolonging the effective time of the drug,reducing the bleeding etc.Beside useful effects of these drugs ,In some cases these agents can cause unwanted complications.Such as vasoconstrictor agents .The aim of this study is the Comparison of heart rate and blood pressure after administration of anesthesia agent with and without Vasoconstrictor. .In a randomized clinical trial, 182 patients reffered for extraction of mandibular molar teeth in dental clinic of Tabriz university of medical sciences who were undergoing in the form of two equal groups.patients were randomizely assigned to one of two groups .we used Lidocaine2%+1:80000 Epinephrine cartridge for one group and Mepivacaine 3% cartridge for the other group.Heart rate Systolic and Diastolic blood pressure was recorded for patients before and after the injection ,all data was analyzed statistically . In this study we studied 182 patients in two groups,the groups were matched for gender and age.the mean heart rate of patients before and after Lidocaine+Epinephrine injection had a significant difference,how ever there was no significant difference in the heart rate of patients before and after Mepivacaine injection.the mean systolic and diastolic blood pressure of patients before and after injection of Lidocaine+Epinephrine was significantly different,the difference between diastolic and systolic blood pressure before and after Mepivacaine injection was not statistically meaningfull. The difference in changes of pulse rate systolic and diastolic blood pressure was significantly different in two groups.Using of local anesthetic agents containing vasopressor agents can lead in hemodynamic changes like increase in blood pressure and puls rate. Although these changes are without complications in many patients but carful using of them in patients with cardiovascular diseases is recommended