Clinical and Microbiological Effects of Photo-activated disinfection Associated with Non-surgical Treatment in Aggressive Periodontitis

Abstract

Aim: The aim of this study was to compare the effectiveness of adjunctive photo-activated disinfectant in the treatment of aggressive periodontitis. Methods: A total of 24 patients with clinical diagnosis of aggressive periodontitis received scaling and root planning (SRP) for periodontal treatment. In a split-mouth design study, the teeth of one quadrant of each arch with 4 mm PD were selected randomly for additional treatment with PAD (test group). The control group consisted of selected teeth of the contralateral quadrant (SRP only). Before any treatment, subgingival plaque samples were collected by an endodontic paper cone for microbiological analysis by real-time PCR. Clinical parameters, including clinical attachment loss (CAL) as primary outcome, plaque index (PI), bleeding on probing (BOP), probing depth (PD) and gingival recession (REC), were measured at baseline and after 90 days. Intergroup and intragroup statistical analyses were performed. Results: Treatment groups showed an improvement in all the clinical parameters and a significant reduction in the counts of periodontopathogen Aggregatibacter actinomycetecommitans at 90 days compared to baseline (P<0.05). None of the periodontal parameters showed significant differences between the two groups (P>0.05). Conclusion: Within the limitations of this study, the results did not show additional benefits from PAD as an adjunctive treatment for patients with aggressive periodontitis