A Comparison of the analgesic effects of Novafen and Ibuprofen in Relieving pains caused by periodontal surgeries

Abstract

Control of post dentistry pain is one of the main issues that the dentists encounter with it, non-steroid anti-inflammatory drugs are more common drugs used for control of pain. Recently, a pharmaceutical compound called noefen has been entered to the market that consists of ibuprofen, acetaminophen and caffeine. Due to necessity of accurate control of pain in periodontal operations and lack of studies in this field the aim of this research is to compare anti pain effect of noafen and ibuprofen in reliving of pain after periodontal surgery. Materials and methods: In a clinical training control random study, 30 patients of candidates of full mouth periodontal operation in the form of two groups consisting of 30 areas (each patient from two areas) were studied. The patients of both groups were the same in terms type of surgery. After operation, group one received the capsule of noafen(35 mg acetaminophen , 200mg ibuprofen and 40 mg caffeine). The second group received ibuprofen 400mg after operation. The drugs were chosen from the same pharmaceutical firm and the patients consumed the prescribed drugs. The levels of pain were studied after 30 minutes, 1 hour, 3 hours after operation (by using VAS) and after 1, 2 and 3 days by using VRS. Findings: The patients were the same in terms of type of operation (p=0.09). Level of variable VAS in minute 30 was significantly less in the group noafen, but in hour 1 and 3 had no significant difference(p=0.321, p=0.547 and p=0.001 respectively). But the level of VRS was less in the first, second and third days in the noafen group (p=0.001, p=0.001, p=0.021). Conclusion: According to the result of this study, it can be concluded that noafen can act effectively after periodontal operation and reduce the patient pain. By this explanation that this control of pain is similar to ibuprofen in the first hours and it is better than ibuprofen in days 1 and 3.