comparactive efficacy of allografts and xenografts in alveolar bone defect

Abstract

Comparison of the success of allografts and xenografts in the reconstruction of alveolar bone defects: A systematic review Masoud Moradi, Farzin Ahmadpour pournaki, Ali Mortazavi, Hosein Azizi

Abstract Background: Due to the increased tendency towards implant rehabilitation, the dimensions of the alveolar ridge are getting more important. Bone grafts are used to promote bone regeneration in ridge augmentation. An autogenous bone graft harvested from the patient is considered as gold standard; However, this method often leads to postoperative discomfort and carries an increased risk of infection at the donor site. Therefore, there is a need for alternative materials, including the use of allogeneic and xenogeneic transplants. Considering the importance of regenerating alveolar bone defects and the variety of bone graft sources, along with the diverse studies examining the effects of each graft type, this study aims to compare the effectiveness of allografts and xenografts in the regeneration of alveolar bone defects in the form of a systematic review. Materials and methods: A systematic literature search was performed until September 2024 without restriction on the start date. Preferred Reporting Items for Systematic Reviews and meta-analysis guidelines were observed for article selection.

Results: Five studies were included. Four studies were randomized clinical trials and one was a retrospective study. The majority of the studies reported no statistically significant difference between the two treatment modalities. Conclusion: Both allografts and xenografts are effective in the reconstruction of alveolar bone defects. Studies involving larger sample sizes and more extensive augmentation procedures are recommended.

Keywords: Alveolar bone loss; Allografts; Xenografts