Relation between HbA1C level and COVI19 Severity and outcome in diabetic patients

Abstract

findings of the first months of 2020 show that most people with covid-19 have comorbidities, the most common of which are diabetes, cardiovascular disease, and high blood pressure. There is no complete information about the role of long-term and appropriate control of blood glucose in the months before contracting the disease of Covid-19, so we decided to organize a study and determine the relationship between HbA1c (representing blood sugar three months ago) and the severity of the disease. Materials and methods: Patients with type 1 and type 2 diabetes who were infected with covid-19 and hospitalized in the non-ICU covid department were included. About 150 diabetic patients were randomly included in the study, and then the patient's tests were extracted from the file and CT scan of the patient's lung was also extracted from the PACS system, and the severity of lung involvement was evaluated separately according to the involvement of each lobe, and finally the patient was evaluated in terms of outcome and mortality. followed up. the information needed for the study was collected using the data collection form that was prepared in advance, and the information was entered into SPSS software after classification, and appropriate statistical tests and analyzes were performed on them, and in all the tests a statistical significance level of 0.05 was considered. Findings: 150 diabetic patients with COVID-19 who were admitted to the hospital were studied. The average age of these patients was 63.82 ± 14.78 years and 53.7% of them were men. The average score of pulmonary involvement in patients with HbA1c below 7, 54.5 ± 10.48, in patients with HbA1C between 7 and 8.5, 11.64 ± 5.27 and in patients with HbA1C above 8.5, It was 11.22 ± 4.87 but no significant difference was reported between the groups in this regard (P=0.661). The prevalence of mortality in patients with glycosylated hemoglobin below 7 was 14.3%, in patients with glycosylated hemoglobin between 7 and 8.5, it was 31% and in patients with glycosylated hemoglobin above 8.5, it was 23%. And in this regard, there was no significant difference between the groups (P=0.329).