Evaluation of Relationship Between Extent of pulmonary artery involvement due to acute pulmonary embolism and one year mortality in Imam Reza Hospital

Abstract

Pulmonary embolism is associated with significant morbidity and mortality. Risk classification (score) in patients with pulmonary thromboembolism is important for better evaluation, monitoring and treatment strategies based on the patient's prognosis. The aim of this study is to comparison of Doppler ultrasonography and shear wave elastography findings with pathology results of patients with nephropathy. Materials and Methods: This research was a descriptive-analytical cross-sectional study and the target population consisted of all patients who were diagnosed with acute pulmonary embolism based on CT angiography of pulmonary vessels during one year from September 2022 to September 2023 at the Imam Reza Medical Training Center in Tabriz (475 patients). The sampling method was census. All patients' information including demographic data, echocardiographic findings and underlying diseases were collected. CT angiography of all patients was performed with a standard method and acceptable quality by a radiologist in both mediastinal and parenchymal views. All CT angiography images were reviewed by a radiologist and all involved branches were reviewed based on the Qanadli scoring index and this scores was recorded. All patients were followed up for one year from the time of diagnosis. The follow-up was in the form of a telephone interview, and if the patient died, the cause was investigated. Results: In this study, the Mean (standard deviation) age of the subjects was 58.31 (±16.6) years. Also, the Mean (SD) of the Qanadli score of these people was 12.97 (±7.3). 22 cases (4.6%) of the studied subjects had chronic thromboembolism. The anatomy involved in these patients was Right in 90 cases (18.9%), Left in 33 cases (6.9%), Bilateral in 316 cases (66.5%), and Bifurcation in 33 cases (6.9%). Out of the total 475 cases of study patients, 408 cases (85.9%) were possible to follow up, of which 87 cases (21.3%) had mortality. The cause of death of the patients under follow-up was unknown in 22 cases (5.4%), pulmonary embolism in 25 cases (6.1%), heart disease in 8 cases (0.2%), trauma in 2 cases (0.5%) and cancer in 32 cases (7.8%). Qanadli score in acute embolism in patients who developed chronic thromboembolism was statistically significantly higher than in patients who not developed chronic thromboembolism (P-value=0.009); On the other hand, there was no statistically significant relationship between the extent of pulmonary artery involvement based on Qanadli scoring in acute embolism with one-year mortality of patients (P-value>0.05).