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dc.contributor.advisorRezaei, Mansour
dc.contributor.authorJamshidi Menbar, Farhang
dc.date.accessioned2024-07-07T08:41:15Z
dc.date.available2024-07-07T08:41:15Z
dc.date.issued2024en_US
dc.identifier.urihttps://dspace.tbzmed.ac.ir:443/xmlui/handle/123456789/70890
dc.description.abstractThe rapid global spread of the novel COVID-19 virus has led to a surge in cases of viral pneumonia and acute respiratory failure, necessitating respiratory support in affected patients. Initially, aggressive ventilation strategies were thought to be beneficial due to the unknown nature of the virus. However, emerging evidence has suggested that timely implementation of non-aggressive ventilation may lead to lower mortality rates compared to aggressive ventilation approaches. Despite this, many aspects related to non-invasive ventilation (NIV) in COVID-19 patients remain poorly understood, warranting further investigation. Therefore, this retrospective cross-sectional/descriptive study aims to explore the relationship between hypercapnia and prognosis in COVID-19 patients treated with NIV, with the goal of informing therapeutic management strategies. Method: A total of 200 COVID-19 patients receiving NIV will be retrospectively enrolled in the study from 1/21/2024 to 5/19/2022. Demographic data, vital signs, initial and peak biochemical values, arterial blood gas measurements, as well as data on disease outcomes, complications, and prognosis will be recorded for each patient. Subsequently, the relationship between hypercapnia and the recorded variables will be analyzed. Results: Analysis of arterial blood gases and oxygenation status revealed no significant difference in the PaO2/FiO2 ratio between the hypercapnic and normocapnic groups. However, the hypercapnic group exhibited significantly lower pH levels, consistent with higher PaCO2 levels. Hospital implications comparison revealed significantly longer durations of hospital and ICU stays, ventilation, and unsuccessful NIV in the hypercapnic group compared to the normocapnic group. Mortality rates did not significantly differ between the two groups.en_US
dc.language.isofaen_US
dc.publisherTabriz University of Medical Sciences, Faculty of Medicineen_US
dc.relation.isversionofhttps://dspace.tbzmed.ac.ir:443/xmlui/handle/123456789/70889en_US
dc.subjectCOVID-19en_US
dc.subjectViral pneumoniaen_US
dc.subjectAcute respiratory failureen_US
dc.subjectRespiratory supporten_US
dc.subjectNon-invasive ventilationen_US
dc.subjectHypercapniaen_US
dc.titleCorrelation of hypercapnia with outcome of NIV in critically ill patients with COVID-19en_US
dc.typeThesisen_US
dc.contributor.supervisorGhamari, Ali Akbar
dc.contributor.supervisorMoharreri, Melorina
dc.identifier.docno6011636en_US
dc.identifier.callno11636en_US
dc.description.disciplineMedicineen_US
dc.description.degreeMD Degreeen_US


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