Comparison of the effect of adding probiotics to orthodontic wax on pain and wounds in patients undergoing fixed orthodontic treatment

Abstract

Ulcers caused by mucosal irritation of fixed orthodontic appliances remain an unsolved problem and need more research to improve the pain caused by orthodontics in orthodontic patients in order to provide better and more comfortable treatment for these patients. The purpose of this study is to investigate the effect of probiotic "Lactogam" on accelerating wound healing and reducing pain and discomfort from orthodontic wounds. . Materials and methods: In this study, 36 patients over 12 years of age and candidates for fixed orthotic treatment were divided into two target groups (n=18) and control groups (n=18). The control group received orthodontic waxes and the target group also received the same orthodontic waxes and "Lactogam" probiotic lozenges from the beginning of the treatment. Indicators such as the number of brushing times, the number of wounds, the amount of pain, the location of the wound and bleeding were recorded and compared between the two groups. The difference between the variables between the groups was checked with proportional statistical tests. In statistical tests, p-value < 0.05 was considered significant. Results: The results showed that the number of brushing times in the target group during 30 days was significantly higher than the control group and the trend of brushing frequency changes was similar in the two groups. On the other hand, in the target group, the average number of wounds almost reached zero after the 8th day of treatment, while this did not happen in the control group even on the 30th day of treatment. In other words, the average number of wounds in the target group was significantly lower than the control group. In the target group, the average pain after the 9th day of treatment almost reached zero, while this did not happen in the control group even on the 30th day of treatment. The average pain in the target group was significantly lower than the control group. In the target group, the average number of days that the patients had ulcers in the mucosa of the cheek, lip and tongue was significantly less than the control group. Conclusion: The experimental findings discussed here support the idea that lactogam probiotic reduces traumatic oral lesions and ulcers in different parts of the mouth, including the mucosa of the cheek, lip, and tongue. Larger clinical trials are encouraged to confirm these findings.