Comparison of Sellaturcica Morphometrics between Healthy Individuals and Patients with Cleft Palate and Lip Referred to Dental School of Tabriz University of Medical Sciences between 2017 and 2020 using CBCT images

Abstract

Introduction Cleft lip and palate is the most common craniofacial malformation. Considering that the morphometric examination of the sella turcica helps to better understand genetic disorders affecting the craniofacial region, the aim of this study was to compare the morphometrics of the sella turcica between healthy individuals and cleft lip and palate patients using CBCT images. Materials and methods In this cross-sectional-analytical and retrospective study, 48 CBCT images of patients with CLP and 48 CBCT images of healthy individuals were selected from the radiology archive of Tabriz Dental School in 2016-2018. CBCT data were entered in NNT viewer, version 8.00 software and were analyzed in sagittal section. The length, depth and diameter of the sella turcica were measured. Shape of the sella turcica was classified in three types (oval, round and flattend). Data was analyzed using SPSS26 software and Mann-Whitney and Chi-square tests. Results There was no significant difference in the length, depth and diameter of the sella turcica in patients with CLP and healthy subjects. The round form was the most frequent in both groups of patients with CLP and healthy individuals. A significant difference was found between the groups in the shape distribution of the sella turcica. In both groups, the dimensions of the sella turcica (length, depth and diameter) were not significantly different between men and women. In both groups, the length of the sella turcica in people <16 years old was significantly less than other age groups; But height and diameter had no significant difference between age groups. Conclusion The morphometrics of sella turcica is similar in people with cleft lip and palate and healthy people.