The Correlation of maternal ophthalmic artery Doppler criteria with maternal clinical finding and fetal birth weight in pregnancies complicated with preeclampsia

Abstract

One of the most important problems during pregnancy is the disorders related to pre-eclampsia, which increases the complications and mortality of the perinatal period and increases the complications of mortality in the mother. Since it seems that PR is the best factor to differentiate preeclampsia from chronic hypertension and determine the severity of preeclampsia. The purpose of this study is to measure the Doppler parameters of the ophthalmic artery in mothers with preeclampsia and investigate its relationship with clinical findings and birth weight of the neonate. Material and Methods: This cross-sectional-analytical study was conducted in 1401 on 68 pregnant women who were hospitalized in the high-risk pregnancy department of Al-Zahra Hospital due to pre-eclampsia. Measurement of various Doppler parameters of ophthalmic artery in pregnant women with pre-eclampsia was done and these parameters were checked with clinical and laboratory findings and percentile of birth weight. Result: The results showed that the mean of all Doppler parameters (except EDV, Peak ratio and SD) in patients with headache is higher than in patients without headache. The difference of these averages did not show a statistically significant difference in any of the parameters between the two groups (P-value>0.05). Also, the values of Peak Ratio (P-value=0.031) and EVD (P-value=0.002) have a significant relationship with the percentile of newborns. The amount of urea has a significant correlation with RI (P-value=0.024), Peak ratio (P-value=0.012) and SD (P-value=0.009). This correlation was negative with RI (r=-0.274) and SD (r=-0.315) and positive with Peak Ratio values (r=0.303). This means that with increasing amount of urea, RI and SD values decrease and Peak Ratio values increase. Also, the level of systolic blood pressure with EDV showed a significant negative correlation (r=-0.296) (P-value=0.014). The amount of proteinuria also had a significant negative correlation (r=-0.271) with SD (P-value=0.025).