Comparıson between clınıcal effects of ıntra-artıcular ozone and intra-articular steroıd injection ın the treatment of chronic ankle osteoarthrıtıs

Abstract

Ankle osteoarthritis is a degenerative disease that leads to joint destruction, pain and decreased function. One of the non-surgical treatments for this disease is intra-articular injection of ozone. In this study, we aimed to compare the therapeutic effect of corticosteroids with ozone in the treatment of grade 3 and 2 ankle osteoarthritis.

Methods and Materials: In this clinical trial, 40 patients with a diagnosis of osteoarthritis of the knee who referred to the physical medicine and rehabilitation clinics of Imam Reza Hospital in Tabriz were included in the study according to the inclusion and exclusion criteria and were randomly divided into two groups. In one group, the amount of triamcinolone and in the other group, ozone was injected into the knee. In the steroid therapy group, patients treated with a mixture of 40 mg of Triamcinolone and 1 mg of lidocaine received 2% of the drug once intra-articularly. C-lidocaine 2% was injected intra-articularly. In the ozone therapy group, 5 cc of ozone with a concentration of 30 μg / ml was injected into the joint with half a cc of 2% lidocaine. Patients were evaluated with the Foot And Ankle Disability Index (FADI) questionnaire at the first visit, one month and six months later for 3 sessions.

Results: Out of 40 patients included in the study, 22 patients were male and 18 patients were female. The results of the present study showed that pain after six months was significantly reduced in the ozone therapy group: P = 0.01 Function was significantly improved after six months in the ozone therapy group P = 0.001 if There was no significant difference between the two groups in any of the factors one month after injection.